Reagent Name
Mouse anti-human SERCA 3 antibody
Immunogen
Human platelet intracellular membranes
Relevance
SERCA 3 is the sarco-endoplasmic reticulum Ca2+ ATPase that sequesters Ca2+ into intracellular stores of mammalian cells. This antibody inhibits Ca2+ sequestration and Ca2+ATPase activity mediated by human SERCA3.
Cross reactivity
Human
Specificity
Epitope has recently been described to be between amino acids 1-236 of human SERCA3. PL/IM430 recognises a 100kDa SERCA3 protein in platelet lysates.
Tested Applications
Western blotting, immunoprecipitation, immunohistochemistry. SERCA3 function blocking antibody. Removal of sodium azide is recommended prior to functional assays.
Raised in
Mouse
Clonality
Monoclonal
Isotype
IgG1
References