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Anti-CSPG4 antibody for the treatment of melanoma

SummaryA chimeric IgE class anti-CSPG4 antibody has been developed which has demonstrated positive results in vitro and in vivo. The antibody is designed to target immune responses directly against melanoma tumour cells, circumventing the broad immune activatory properties of currently approved immunotherapies.Figure: CSPG4 IgE restricts growth of an...

Published: 11/22/2016 | Updated: 5/8/2014 | Inventor(s): Sophia Karagiannis, Frank Nestle, Andrew Beavil

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Category(s): Therapeutics