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Pentraxin 3 (PTX3) oxidation state as Prognosis Marker for Sepsis

Technology Overview:A global, unbiased, cardiac tissue-based proteomics approach for biomarker discovery in a mouse model of sepsis identified pentraxin 3 (PTX-3) as one of the most differentially expressed proteins in cardiac tissue from septic mice. PTX-3 accumulated as an octamer due to disulphide-bond formation, most notably in heart, aorta, kidney...

Published: 11/22/2016 | Updated: 11/22/2016 | Inventor(s): Manuel Mayr, Friederike Cuello

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Category(s): Diagnostics