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Human Thyrotrophin Receptor Monoclonal Antibody - Clone 2C11

The human thyrotrophin receptor (TSHR) is found primarily in epithelial cells of thyroid follicles where it induces (by cAMP) the phospholipase C and protein kinase A signal transduction pathways. TSHR is the major pathogenic autoantigen in human autoimmune thyroid Graves’ disease.LanesTSHRGlycosylated TSHRTSHR - GSTResidues 125-369 TSHR - GSTProduct...

Published: 11/22/2016 | Updated: 5/8/2014 | Inventor(s): Philip Shepherd

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Category(s): Research Tools - Membrane receptors

Human Thyrotrophin Receptor Monoclonal Antibody - Clone 4C1

Research tool forWestern blottingImmunoprecipitationFlow cytometryImmunohistochemistry (frozen section)Inhibits binding of TSH to TSH receptor by 70-80%.The human thyrotrophin receptor (TSHR) is found primarily in epithelial cells of thyroid follicles where it induces (by cAMP) the phospholipase C and protein kinase A signal transduction pathways. ...

Published: 11/22/2016 | Updated: 5/8/2014 | Inventor(s): Philip Shepherd, Alan Johnstone

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Category(s): Research Tools - Membrane receptors

Human Thyrotrophin Receptor Monoclonal Antibody - Clone 3B12

Research tool for:Immunoblotting Immunoprecipitation Flow cytometry Immunohistochemistry (frozen section)Product TypeHybridoma for monoclonal antibodyImmunogenBacterially expressed extracellular domain (residues 1-415) of human TSHR fused to GSTCross ReactivityCross-reacts with human and theoretically with rat, pig, sheep, mouse, dog, catSpecificityDetects...

Published: 11/22/2016 | Updated: 5/8/2014 | Inventor(s): Philip Shepherd

Keywords(s):

Category(s): Research Tools - Membrane receptors